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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
23.33
Human Site:
T900
Identified Species:
39.49
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
T900
S
I
Q
C
F
Q
N
T
E
A
G
S
P
T
I
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
T900
S
I
Q
C
F
Q
N
T
E
A
G
S
P
T
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
T997
S
I
Q
C
F
Q
N
T
E
A
G
S
P
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
T894
S
I
Q
R
F
Q
N
T
E
A
G
S
P
T
I
Rat
Rattus norvegicus
NP_001099948
974
110023
T865
S
I
Q
C
F
Q
N
T
D
A
G
S
P
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
L804
S
A
A
S
R
V
F
L
M
D
P
A
W
N
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
P890
A
I
Q
S
F
Q
R
P
D
A
Q
S
P
T
I
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
S835
A
I
E
D
F
Q
D
S
T
P
G
S
P
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
R957
I
V
N
E
F
N
D
R
N
N
Q
K
R
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
N979
A
I
R
E
F
S
S
N
D
P
D
S
P
Q
I
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
V719
N
L
A
V
A
S
R
V
Y
L
L
E
P
W
W
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
V801
N
L
T
A
A
S
R
V
Y
L
F
D
P
W
W
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
Q710
L
N
L
C
E
A
S
Q
V
F
I
L
D
P
W
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
T1117
V
L
T
E
F
Q
S
T
N
K
F
C
V
L
L
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
6.6
N.A.
60
53.3
N.A.
6.6
N.A.
N.A.
33.3
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
13.3
N.A.
73.3
80
N.A.
26.6
N.A.
N.A.
60
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
20
P-Site Similarity:
20
N.A.
N.A.
20
13.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
8
15
8
15
8
0
0
0
43
0
8
0
0
0
% A
% Cys:
0
0
0
36
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
8
0
0
15
0
22
8
8
8
8
0
0
% D
% Glu:
0
0
8
22
8
0
0
0
29
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
72
0
8
0
0
8
15
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
43
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
58
0
0
0
0
0
0
0
0
8
0
0
0
58
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% K
% Leu:
8
22
8
0
0
0
0
8
0
15
8
8
0
8
15
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
15
8
8
0
0
8
36
8
15
8
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
15
8
0
72
8
8
% P
% Gln:
0
0
43
0
0
58
0
8
0
0
15
0
0
8
0
% Q
% Arg:
0
0
8
8
8
0
22
8
0
0
0
0
8
0
0
% R
% Ser:
43
0
0
15
0
22
22
8
0
0
0
58
0
0
0
% S
% Thr:
0
0
15
0
0
0
0
43
8
0
0
0
0
50
0
% T
% Val:
8
8
0
8
0
8
0
15
8
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
15
22
% W
% Tyr:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _